Live demo · Memory consolidation · Senescence biomarker panel

When does a biomarker note become durable science?

Three independent IPF cohorts each cite overlapping senescence markers. Pick a cohort to see its own episode note, or view the consolidated schema Smriti forms once replay, context diversity, and recency clear the threshold — with the disputed marker flagged, never deleted.

Choose a view
p16INK4a
0.71 · replicated
MMP-7
0.64 · replicated
IL-6
0.68 · disputed
✓
Verdict: Promoted to schema_ipf_panel_v1
Source episodes
n_ipf_cohortA, n_ipf_cohortB, n_ipf_cohortC
Consolidation score
0.00 → 0.79 · promoted
Cluster similarity
0.86 across 3 episodes
Contradiction
IL-6 flagged — confounded by infection (Cohort C)
Policy
Conservative — flag only, human review required
Audit event
promoted_to_schema · consolidation_events row written

The human-approval path (shipped)

Conservative policy = flag only, human review, source episodes preserved. Notes are never deleted. Schema formation waits on an explicit approve.

# Step 1: Score episodes by replay frequency + centrality + context diversity
$ smriti consolidate --dry-run --policy conservative
─── replay signal, senescence panel ─────────
episode  n_ipf_cohortA  access=14  contexts=3  score=0.71
episode  n_ipf_cohortB  access=9   contexts=2  score=0.64
episode  n_ipf_cohortC  access=11  contexts=3  score=0.68  ⚠ IL-6 disputed

# Step 2: Review flagged schema candidates
$ smriti proposals
─── pending schema candidates ───────────────
schema_candidate_001
  source_episodes    n_ipf_cohortA, n_ipf_cohortB, n_ipf_cohortC
  similarity         0.86 across 3 episodes
  replicated         p16INK4a (0.71), MMP-7 (0.64)
  flagged            IL-6 — confounded by infection (Cohort C)

# Step 3: Human approves → schema formed with full lineage
$ smriti approve schema_candidate_001
✓ Created schema_ipf_panel_v1
  source episodes preserved (not deleted)
  audit event written: promoted_to_schema
  lineage: schema_sources table populated

Questions: hello@bio-sync.tech

Every schema your agent forms should point back to the exact evidence — and never silently erase a dissenting result. Smriti makes that the default.
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